Sermorelin is a synthetic peptide corresponding to the first 29 amino acids of endogenous growth hormone-releasing hormone (GHRH 1–29 NH₂), representing the shortest fully bioactive fragment of the native molecule. It binds to GHRH receptors on anterior pituitary somatotrophs, stimulating the natural pulsatile release of endogenous growth hormone through cAMP-dependent signaling. As a research tool, sermorelin has been used extensively to investigate somatotropic axis dynamics and the regulation of the GH/IGF-1 feedback loop.
| Molecular Formula | C149H246N44O42S |
| Molecular Weight | 3357.97 g/mol |
| Sequence | Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH2 |
| CAS Number | 86168-78-7 |
| Appearance | White to off-white lyophilized powder |
Long-term (Lyophilized)
Store lyophilized powder at -20°C. Protect from light and moisture.
After Reconstitution
Once reconstituted, store at 4°C.
Freeze-Thaw Cycles
Avoid repeated freeze-thaw cycles.
Research Use Only — This product is intended for laboratory use only. Follow proper safety protocols when handling peptides.
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Disclaimer: This product is intended for research and laboratory use only. Not for human consumption. Not intended to diagnose, treat, cure, or prevent any disease. Not evaluated by the FDA.
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